Article

<i>Af</i> Rip3, a RIP3-like kinase, is identified as a key modulator of necroptotic death in <i>Aspergillus fumigatus</i>

2020-03-25

Abstract excerpt

Aspergillus fumigatus exhibits autophagic and necroptotic process when its GPI anchor synthesis is suppressed. A putative kinase (AFUA_6G02590) is found to be overexpressed in response to GPI anchor suppression and identified as a RIP3-like protein, namely Af Rip3. To elucidate its function, in this study a Af rip3 -overexpressing strain OE-Af rip3 was constructed. Although OE-Af rip3 strain exhibited an incre...

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Literature Corpus work: 57c80445-d357-59f6-af73-a3b5fc873cdc
DOI: 10.1101/2020.03.25.007617

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