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Article

Survival strategies of yeast and filamentous fungi against the antifungal protein AFP.

The Journal of biological chemistry - 22 Apr 2011

Ouedraogo Jean Paul, Hagen Silke, Spielvogel Anja, Engelhardt Susanne, Meyer Vera

Abstract excerpt

The activities of signaling pathways are critical for fungi to survive antifungal attack and to maintain cell integrity. However, little is known about how fungi respond to antifungals, particularly if these interact with multiple cellular targets. The antifungal protein AFP is a very potent inhibitor of chitin synthesis and membrane integrity in filamentous fungi and has so far not been reported to interfere...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21343301
DOI: 10.1074/jbc.M110.203588
PMCID: PMC3077587

Genes

AFP

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