Article

Dynamic interplay between sortilin and syndecan-1 drives a metabolic switch during prostate cancer progression

2023-03-27

Abstract excerpt

Prostate cancer (PCa) development and progression relies on the programming of glucose and lipid metabolism, and this involves alterations in androgen receptor expression and signalling. Defining the molecular mechanism that underpins this metabolic programming will have direct significance for patients with PCa who have a poor prognosis. Here we show that there is a dynamic balance between sortilin and syndecan-1...

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Identifiers and source

Literature Corpus work: 56ec7e57-3d1e-55b4-9cb3-ca133d703a9c
DOI: 10.21203/rs.3.rs-2693853/v1

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