Article

Basal stem cell fate specification is mediated by SMAD signaling in the developing human lung

2018-11-04

Abstract excerpt

Basal stem cells (basal cells), located in the bronchi and trachea of the human lung epithelium, play a critical role in normal airway homeostasis and repair, and have been implicated in the development of diseases such as cancer 1-4 . Additionally, basal-like cells contribute to alveolar regeneration and fibrosis following severe injury 5-8 . However, the developmental origin of basal cells in humans is unclear...

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Literature Corpus work: 56e7a582-d328-548a-92f4-02f4bbced15c
DOI: 10.1101/461103

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