Article

Antiretroviral treatment-induced decrease in immune activation contributes to reduced susceptibility to tuberculosis in HIV-1-TB co-infected persons

2020-11-16

Abstract excerpt

Antiretroviral treatment (ART) reduces the risk of developing active tuberculosis (TB) in HIV-1 co-infected persons. In order to understand host immune responses during ART in the context of Mycobacterium tuberculosis (Mtb) sensitization, we performed RNAseq analysis of whole blood-derived RNA from HIV-1 infected patients during the first 6 months of ART. A significant fall in RNA sequence abundance of the Hallmar...

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Literature Corpus work: 56d4d1c5-b7e3-5af2-999a-692e473e6efb
DOI: 10.1101/2020.11.13.20231274

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