Article

Histone-like Nucleoid-structuring Protein (H-NS) Regulatory Role in Antibiotic Resistance in Acinetobacter Baumannii

2021-07-14

Abstract excerpt

In the multidrug resistant (MDR) pathogen Acinetobacter baumannii the global repressor H-NS was shown to modulate the expression of genes related to quorum sensing, biosynthetic pathways, cell adhesion, virulence, and autotransporters. In addition, H-NS is involved in stress response and its inactivation results in an increased resistance to colistin, and in a hypermotile phenotype an altered stress response. To f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56d15214-47b8-53b9-ac84-ac0ecdf58345
DOI: 10.21203/rs.3.rs-690008/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Histone-like Nucleoid-structuring Protein (H-NS) Regulatory Role in Antibiotic Resistance in Acinetobacter BaumanniiDOI 10.21203/rs.3.rs-690008/v1Read

Histone-like nucleoid-structuring protein (H-NS) regulatory role in antibiotic resistance in Acinetobacter baumannii.Semantic proximity Read

Human Serum Albumin (HSA) Regulates the Expression of Histone-like Nucleoid Structure Protein (H-NS) in Acinetobacter baumanniiSemantic proximity Read

H-NS plays a role in expression of Acinetobacter baumannii virulence features.Semantic proximity Read

H-NS is a bacterial transposon capture proteinSemantic proximity Read

RNA-seq analysis identifies new genes regulated by the histone-like nucleoid structuring protein (H-NS) affecting Vibrio cholerae virulence, stress response and chemotaxis.Semantic proximity Read

A Histone-Like Nucleoid Structuring Protein Regulates Several Virulence Traits in Burkholderia multivorans.Semantic proximity Read

H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF.Semantic proximity Read

NsaRS is a cell-envelope-stress-sensing two-component system of Staphylococcus aureusSemantic proximity Read

Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli.Semantic proximity Read

Nucleoid-associated proteins shape the global protein occupancy and transcriptional landscape of a clinical isolate of <i>Vibrio cholerae</i>Semantic proximity Read

Emergence of High-Level Colistin Resistance in an Acinetobacter baumannii Clinical Isolate Mediated by Inactivation of the Global Regulator H-NSSemantic proximity Read

DksA is a central regulatory switch for stress protection and virulence in Acinetobacter baumanniiSemantic proximity Read