Article

A Biphasic Effect of Alcohol on Endothelial Plasticity Through Regulation of Endothelial-to-Mesenchymal Transition

2026-04-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Alcohol consumption influences cardiovascular disease, but whether it does so by affecting endothelial plasticity is unknown. We tested whether alcohol regulates endothelial-to-mesenchymal transition (EndMT) to influence arterial pathology. <h4>Methods</h4> HCAEC and HUVEC were exposed to inflammatory cytokines (TGFβ ± IL1β) or hypoxia in the presence of ethanol (0-100 mM)....

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Literature Corpus work: 56c8b496-436c-5185-9034-d689d5ed7a31
DOI: 10.64898/2026.04.14.718463

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