Back to search

Article

Chitosan oligosaccharide suppresses osteosarcoma malignancy by inhibiting CEMIP via the PI3K/AKT/mTOR pathway

2023-08-02

Abstract excerpt

<title>Abstract</title> <p>Osteosarcoma is a malignant bone tumor that is prone to metastasize early and primarily affects children and adolescents. Cell migration-inducing protein (CEMIP) plays a crucial role in the progression and malignancy of various tumor diseases, including osteosarcoma. Chitosan oligosaccharide (COS), an oligomer isolated from chitin, has been found to have significant anti-tumor activity...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
56c6d0f0-b199-54b4-ba14-974965ba7f6d
DOI
10.21203/rs.3.rs-3170206/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 9 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Chitosan oligosaccharide suppresses osteosarcoma malignancy by inhibiting CEMIP via the PI3K/AKT/mTOR pathwayDOI 10.21203/rs.3.rs-3170206/v1
Glucosamine increases the expression of YKL-40 and osteogenic marker genes in hMSC during osteogenic differentiationSemantic proximity
Paris polyphyllaSuppresses Proliferation and Vasculogenic Mimicry of Human Osteosarcoma Cells and Inhibits Tumor GrowthIn VivoSemantic proximity
The inhibitory effects and mechanisms of 3,6-O-sulfated chitosan against human papillomavirus infection.Semantic proximity
The long noncoding RNA cancer susceptibility candidate 2 inhibits tumor progression in osteosarcomaSemantic proximity
Costunolide inhibits osteosarcoma growth and metastasis via suppressing STAT3 signal pathwaySemantic proximity
A novel cell-wall polysaccharide derived from the stipe of Agaricus bisporus inhibits mouse melanoma proliferation and metastasisSemantic proximity
A polysaccharide from Pinellia ternata inhibits cell proliferation and metastasis in human cholangiocarcinoma cells by targeting of Cdc42 and 67 kDa Laminin Receptor (LR)Semantic proximity
Bruceine D inhibits tumor growth and stem cell‐like traits of osteosarcoma through inhibition of STAT3 signaling pathwaySemantic proximity
Polyacetylene Isomers Isolated from Bidens pilosa L. Suppress the Metastasis of Gastric Cancer Cells by Inhibiting Wnt/β-Catenin and Hippo/YAP Signaling PathwaysSemantic proximity
Select a neighboring publication to make it the new centre.