Article
The inhibitory effects and mechanisms of 3,6-O-sulfated chitosan against human papillomavirus infection.
Carbohydrate polymers - 15 Oct 2018
Gao Yanyun, Liu Wei, Wang Wei, Zhang Xiaoshuang, Zhao Xia
Abstract excerpt
High-risk human papillomavirus (HPV) infection can lead to the development of cervical cancers that are a significant health burden worldwide. The heparin-like polysaccharides such as dextran sulfate and carrageenan were reported to be able to prevent the binding of HPV to the cell surface. In this study, a 3,6-O-sulfated chitosan (36S) was prepared, and its anti-HPV effects were explored. The results showed that...
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