Article

Fast and exact single and double mutation-response scanning of proteins

2020-10-25

Abstract excerpt

Studying the effect of perturbations on protein structure is a basic approach in protein research. Important problems, such as predicting pathological mutations and understanding patterns structural evolution, have been addressed by computational simulations based on modelling mutations as forces and predicting deformations using the Linear Response Approximation. In single mutation-response scanning simulations,...

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Literature Corpus work: 56a5404f-2ac6-5747-b766-bfa986ac65ce
DOI: 10.1101/2020.10.23.352955

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