Article

Optimizing the IMQ model: Deep characterization of the human TLR7 response for early drug development

2024-07-23

Abstract excerpt

<title>Abstract</title> <p>Purpose Imiquimod (IMQ; brand name Aldara®) is a registered topical agent that has been proven to induce local inflammation via the Toll-like receptor (TLR)7 pathway. The purpose of this study was to characterize TLR7-mediated inflammation following 7 days (168h) of topical IMQ exposure in healthy volunteers, and to compare the effects of short exposure (48h-72h) with prolonged exposur...

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Literature Corpus work: 56a31758-dc1b-5acf-893b-610b4faaef45
DOI: 10.21203/rs.3.rs-4655296/v1

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