Article

AAV-HDV an Attractive Platform for the In Vivo Study of HDV Biology and Mechanism of Disease Pathogenesis

2021-03-16

Abstract excerpt

Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis but little is known about the molecular mechanisms involved. The recently developed HDV mouse model based on the delivery of HDV replication-competent genomes using adeno-associated vectors (AAV) develop a liver pathology very similar to the human disease, and allowed us to perform mechanistic studies. We have generated different...

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Literature Corpus work: 56923d69-a8dc-56ac-80fe-4580a67248c5
DOI: 10.20944/preprints202103.0411.v1

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