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ISEBC: Using A Novel Breast Cancer Tertiary Lymphoid Structures Signature To Build An Immune-favourable Status Evaluator For Breast Cancer

2024-12-09

Abstract excerpt

<title>Abstract</title> <p>Tertiary lymphoid structures (TLSs), as a special type of immune-infiltrated region in tumor tissues, plays an important role in benefiting from immunotherapy or improving immune state of breast cancer patient. However, breast cancer-specific TLS signature gene sets are still lacking. Therefore, we extracted gene features with machine learning algorithm LightGBM, and differential expres...

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Literature Corpus work: 567d485d-d4f3-5a35-8557-1ac02ecd1540
DOI: 10.21203/rs.3.rs-5376285/v1

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