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Stroke prevention by traditional Chinese medicine? A genetic algorithm, support vector machine and molecular dynamics approach

2011-01-01

Abstract excerpt

Phosphodiesterase 4D (PDE4D) has been identified be a promising target which associate with stroke, which is one of the top 3 leading of death and main leading cause of adult disability in US. In this study, we applied virtual screening on the world's largest traditional Chinese medicine (TCM) database (http://tcm.cmu.edu.tw;1 C. Y. C. Chen, PLoS One, 2011, 6, e15939) for natural compounds that inhibit PDE4D funct...

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Literature Corpus work
56502c44-e738-5936-a87e-09afe2d0de24
DOI
10.1039/c0sm01548b
Open publication

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