Article

A chronopharmacology-friendly multi-target therapeutics based on AI: the example of therapeutic hypothermia

2022-03-10

Abstract excerpt

Nowadays, the complexity of disease mechanisms and inadequacy of single-target therapies in restoring the biological system has inevitably instigated the strategy of multi-target therapeutics with the application of hybrid and chimeric drugs. However, the related method is still unable to solve the conflicts between targets or between drugs. With the release of high-precision protein structure prediction artificia...

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Literature Corpus work: 0b71969d-2810-516c-91fd-e5bc8ffb4375
DOI: 10.1101/2022.03.07.22271997

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