Article

Activation of LncRNA HOTAIR by STAT3 Promotes Gefitinib Resistance and Tumourigenesis by Targeting MicroRNA-216a in NSCLC

2021-08-03

Abstract excerpt

<title>Abstract</title> <p>Background: Gefitinib resistance has become a major obstacle for cancer therapy of non-small cell lung cancer (NSCLC). Exosome-mediated transfer of long noncoding RNAs (lncRNAs) is associated with the drug-resistance in various tumors. However, the role of NSCLC-specific exosomal lncRNAs remains largely unknown. The aim of this study is to explore the role of exosomal Hox transcript an...

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Literature Corpus work: 21d80d71-66fb-55f7-968b-b6a5c5c9dc25
DOI: 10.21203/rs.3.rs-703543/v1

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