Article

Tertiary lymphoid organ neogenesis in grey matter pathology in multiple sclerosis

2015-01-01

Abstract excerpt

Chronic meningeal inflammation is suggested to contribute to the progression of secondary progressive multiple sclerosis (SPMS) in part by driving cortical grey matter pathology. The presence of tertiary lymphoid organ-like (TLO) structures in a large proportion of SPMS cases is associated with faster clinical progression and more severe cortical pathology, suggesting that TLO neogenesis and chronic meningeal infl...

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Literature Corpus work: 55d6007b-9189-5275-9c59-53ed666f82df
DOI: 10.25560/30813

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