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Provision of Preferred Nutrients to Macrophages Enables <i>Salmonella</i> to Replicate Intracellularly Without Relying on Type III Secretion Systems

2025-05-15

Abstract excerpt

Intracellular survival and replication within macrophages are key virulence determinants of Salmonella enterica serovar Typhimurium. This phenomenon is traditionally attributed to the activity of its two Type III Secretion Systems (T3SS) and their associated effectors. A critical challenge for these bacteria is acquiring nutrients from inside the host cell. Thus, they modulate the metabolism of host cells to repl...

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Literature Corpus work
55d10169-53e7-5d2d-8939-5557eb385084
DOI
10.1101/2025.05.15.653970
Open publication

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Provision of Preferred Nutrients to Macrophages Enables <i>Salmonella</i> to Replicate Intracellularly Without Relying on Type III Secretion SystemsDOI 10.1101/2025.05.15.653970
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