Article
Analysis of cardiomyocyte nuclei in human cardiomyopathy reveals orientation dependent defects in shape
2020-08-15
Abstract excerpt
Cardiomyopathies are progressive diseases of heart muscle often caused by mutations in genes encoding sarcomeric, cytoskeletal and nucleoskeletal proteins though in many cases the cause of disease is not identified. Whilst nucleus hypertrophy has been described, it is not known whether nucleus shape changes are a general feature of cardiomyopathy. Due to the rod-shaped nature of cardiomyocytes and their elliptical...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 559acfd7-5b70-50c5-8f90-48475e51c9f5
- DOI
- 10.1101/2020.08.14.20168310