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Pan-cancer Analysis Predicts Kindlin-associated Global Mechanochemical Perturbation

2022-11-01

Abstract excerpt

Kindlins are mechanosensitive adapter proteins that connect extracellular mechanical cues to intracellular chemical events. Any alterations in these proteins thus alter cellular signaling, which could result in cancer progression. However, their involvement in global mechanochemical signals remains elusive in cancers. Here we analyze pan-cancer samples to decipher how kindlin alterations aid cancer progression. We...

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Literature Corpus work
559856f1-6c6c-5413-8e4e-4b827987ad72
DOI
10.1101/2022.10.31.514453
Open publication

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Pan-cancer Analysis Predicts Kindlin-associated Global Mechanochemical PerturbationDOI 10.1101/2022.10.31.514453
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