Article
Pan-cancer Analysis Predicts Kindlin-associated Global Mechanochemical Perturbation
2022-11-04
Abstract excerpt
<title>Abstract</title> <p>Kindlins are mechanosensitive adapter proteins that connect extracellular mechanical cues to intracellular chemical events. Any alterations in these proteins thus alter cellular signaling, which could result in cancer progression. However, their involvement in global mechanochemical signals remains elusive in cancers. Here we analyze pan-cancer samples to decipher how kindlin alteration...
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Identifiers and source
- Literature Corpus work
- 6842628b-4fe0-5871-86a1-0a5c4ff3e122
- DOI
- 10.21203/rs.3.rs-2129202/v1