Article

Nipah virus matrix protein utilizes cortical actin to stabilize the virus assembly sites and promote budding

2025-01-28

Abstract excerpt

Several families of enveloped viruses assemble and bud from the host cell plasma membranes (PM), including paramyxoviruses. Nipah virus (NiV) is a deadly zoonotic paramyxovirus causing yearly outbreaks in Southeast Asia with >75% mortality. NiV encodes matrix proteins (M) that drive assembly and budding. NiV-M forms dimers and interacts with membrane lipids in the host cell’s PM for budding. Using single-molecule...

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Identifiers and source

Literature Corpus work: 557569a7-f98f-5f75-a8d0-287e4631bbca
DOI: 10.1101/2025.01.27.635114

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