Back to search

Article

pyMKM: An Open-Source Python Package for Microdosimetric Kinetic Model Calculation in Research and Clinical Applications

2025-10-06

Abstract excerpt

Among existing radiobiological models, the MKM and its extensions (SMK and OSMK) have demonstrated strong predictive capabilities but remain computationally demanding. To address this, we present pyMKM, an open-source Python package for the generation of microdosimetric tables and radiobiological quantities based on these models. The package includes modules for track structure integration, saturation and stochast...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
54dd2c85-9d9f-5f9c-be67-00a2bb4a5a41
DOI
10.20944/preprints202510.0419.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
pyMKM: An Open-Source Python Package for Microdosimetric Kinetic Model Calculation in Research and Clinical ApplicationsDOI 10.20944/preprints202510.0419.v1
The Mayo Clinic Florida Microdosimetric Kinetic Model of Clonogenic Survival: Application to Various Repair-Competent Rodent and Human Cell LinesSemantic proximity
Influence of LET on Low-dose Radiation Responses: Signatures of Hyper-radiosensitivity after High-LET Irradiation.Semantic proximity
Modelling the HPRT-gene mutation induction of particle beams: systematicin vitrodata collection, analysis and microdosimetric kinetic model implementation.Semantic proximity
Development of a Temperature-Dependent Chemical Simulation Code based on PHITS for Water Radiolysis from 0 to 350°CSemantic proximity
NanOx, a new model to predict cell survival in the context of particle therapySemantic proximity
A Multiscale Computational Framework for the <sup>28</sup> Mg Radio-Cofactor Hypothesis: Conditional Emergence of Coordinated Disruption under the Gate ConditionSemantic proximity
Image-Guided Targeting of Mitochondrial Metabolism Sensitizes Pediatric Malignant Rhabdoid Tumors to Low Dose RadiotherapySemantic proximity
Tumour metabolic heterogeneity discrimination by video thermometry and concanamycin-sensitive proton pump measurements: Old tools integrated into advanced preclinical studiesSemantic proximity
Applications of amorphous track models in radiation biology.Semantic proximity
Effects of track structure and cell inactivation on the calculation of heavy ion mutation rates in mammalian cells.Semantic proximity
An investigation on the capabilities of the PENELOPE MC code in nanodosimetrySemantic proximity
Mapping neutron biological effectiveness for DNA damage induction as a function of incident energy and depth in a human sized phantomSemantic proximity
Select a neighboring publication to make it the new centre.