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Article

NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway

14 Jan 2022

Abstract excerpt

Glioblastoma (GBM) is one of the most lethal primary brain tumor with a poor median survival less than 15 months. Despite the development of the clinical strategies over the decades, the outcomes for GBM patients remain dismal due to the strong proliferation and invasion ability and the acquired resistance to radiotherapy and chemotherapy. Therefore, developing new biomarkers and therapeutic strategies targeting...

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PMID: 35031599
DOI: 10.1038/s41419-022-04512-6

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