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Article

A Variant-Resistant Linear Epitope in the SARS-CoV-2 Nucleocapsid Protein for Antigen Detection

2026-07-10

Abstract excerpt

We previously generated a mouse monoclonal antibody, N179, against the SARS-CoV-2 nucleocapsid (N) protein and developed a colloidal gold-based immunochromatographic test strip. This assay achieved a detection limit of 2 ng/mL and displayed 98% concordance with RT-qPCR results. However, the precise epitope recognized by mAb N179 had not been defined. Using a panel of GST-fused N protein truncation fragments, we ma...

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Literature Corpus work
54aa9263-2396-5d3e-830c-44c49bf10c17
DOI
10.64898/2026.07.10.737673
Open publication

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A Variant-Resistant Linear Epitope in the SARS-CoV-2 Nucleocapsid Protein for Antigen DetectionDOI 10.64898/2026.07.10.737673
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