Article
Design and Development of an Antigen Test for SARS-CoV-2 Nucleocapsid Protein to Validate the Viral Quality Assurance Panels.
Viruses - 24 Apr 2024
Ray Partha, Ledgerwood-Lee Melissa, Brickner Howard, Clark Alex E, Garretson Aaron, Graham Rishi, Van Zant Westley, Carlin Aaron F, Aronoff-Spencer Eliah S
Abstract excerpt
The continuing mutability of the SARS-CoV-2 virus can result in failures of diagnostic assays. To address this, we describe a generalizable bioinformatics-to-biology pipeline developed for the calibration and quality assurance of inactivated SARS-CoV-2 variant panels provided to Radical Acceleration of Diagnostics programs (RADx)-radical program awardees. A heuristic genetic analysis based on variant-defining...
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