Article

Intra-slide calibration technology improves immunohistochemical harmonization within and between anatomic pathology laboratories

2026-06-08

Abstract excerpt

The reproducibility of immunohistochemistry in tumor tissue analysis across reference labs remains a persistent challenge. We tested the extent to which an intra-slide calibration technology mitigated discprepencies in inter-laboratory assays of p53 immunohistochemical (IHC) reactions in brain biopsies of glioblastoma (GB), IDH-wildtype. Intra-slide calibration technologies apply a 0-100% concentration scale incor...

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Identifiers and source

Literature Corpus work: 5480bd79-8849-5148-94d0-fa210960f8a6
DOI: 10.64898/2026.06.04.730099

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