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Article

Impact of tissue staining and scanner variation on the performance of pathology foundation models: a study of sarcomas and their mimics

2025-08-22

Abstract excerpt

Histopathological analysis is considered the gold standard for the diagnosis and prognostication of cancer. Recent advances in AI, driven by large-scale digitisation and pan-cancer foundation models, are opening new opportunities for clinical integration. However, it remains unclear how robust these foundation models are to real-world sources of variability, particularly in H&E staining and scanning protocols. In...

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Literature Corpus work
20a296e8-f691-5cd7-a5ee-8cdf95a97c98
DOI
10.1101/2025.08.18.670932
Open publication

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Impact of tissue staining and scanner variation on the performance of pathology foundation models: a study of sarcomas and their mimicsDOI 10.1101/2025.08.18.670932
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