Article

<i>Enterococcus faecalis</i> delivers Obg GTPase via extracellular vesicles to instigate mTOR activity and promote HCC tumorigenesis

2025-10-01

Abstract excerpt

Hepatocellular carcinoma (HCC) is a malignant tumor that has been associated with dysbiosis of the gut microbiota. However, how the gut microbiota plays an oncogenic role in HCC remains largely unknown. Here, we show that Enterococcus faecalis (E. faecalis) is highly enriched in liver tumor tissues and is positively correlated with pathogenesis of HCC. E. faecalis promotes liver cancer cell proliferation, protei...

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Identifiers and source

Literature Corpus work: 53dc37cf-2d00-558b-80d4-a719841ff677
DOI: 10.1101/2025.09.30.653999

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<i>Enterococcus faecalis</i> delivers Obg GTPase via extracellular vesicles to instigate mTOR activity and promote HCC tumorigenesisDOI 10.1101/2025.09.30.653999Read

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