Article

The assessment of single nucleotide polymorphisms in the ß-tubulin genes in human soil-transmitted helminths exposed to different pressure with benzimidazole drugs

2024-06-04

Abstract excerpt

<h4>Background</h4> We aimed to gain insights into the role of known single nucleotide polymorphisms (SNPs) in codons 167, 198 and 200 of the ß-tubulin gene as markers for possible benzimidazole resistance in human soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura , Necator americanus and Ancylostsoma duodenale ). <h4>Methods</h4> Firstly, we determined the analytical performance of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 53c3d4db-f25a-540f-8f83-fc4056c4d06d
DOI: 10.1101/2024.06.04.597280

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The assessment of single nucleotide polymorphisms in the ß-tubulin genes in human soil-transmitted helminths exposed to different pressure with benzimidazole drugsDOI 10.1101/2024.06.04.597280Read

Assays to detect beta-tubulin codon 200 polymorphism in Trichuris trichiura and Ascaris lumbricoides.Semantic proximity Read

Rapid Genotyping of β-tubulin Polymorphisms in Trichuris trichiura and Ascaris lumbricoides.Semantic proximity Read

Deep-amplicon sequencing of the complete beta-tubulin gene in Trichuris trichiura before and after albendazole treatment.Semantic proximity Read

Association between response to albendazole treatment and β-tubulin genotype frequencies in soil-transmitted helminths.Semantic proximity Read

Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus pooled eggs.Semantic proximity Read

Benzimidazole resistance survey for Haemonchus, Teladorsagia and Trichostrongylus in three European countries using pyrosequencing including the development of new assays for Trichostrongylus.Semantic proximity Read

Benzimidazole Resistance-Associated Mutations in the β-tubulin Gene of Hookworms: A Systematic Review.Semantic proximity Read

Benzimidazole Resistance-Associated Mutations in the β-tubulin Gene of Hookworms: A Systematic ReviewSemantic proximity Read

Development of high throughput method for the analysis of anthelmintic resistance allele frequencies in field populations of gastrointestinal nematodesSemantic proximity Read

Genetic variation in codons 167, 198 and 200 of the beta-tubulin gene in whipworms (Trichuris spp.) from a range of domestic animals and wildlife.Semantic proximity Read

Deep amplicon sequencing screening benzimidazole resistance associated specific single nucleotide polymorphisms in isotype-1 β-tubulin from trichostrongyloids on ruminant farms in northeast Germany.Semantic proximity Read

Absence of detectable benzimidazole-resistance associated alleles in Haemonchus placei in cattle in Nigeria revealed by pyrosequencing of β-tubulin isotype 1.Semantic proximity Read