Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between response to albendazole treatment and β-tubulin genotype frequencies in soil-transmitted helminths.

PLoS neglected tropical diseases - 1 Jan 2013

Diawara Aïssatou, Halpenny Carli M, Churcher Thomas S, Mwandawiro Charles, Kihara Jimmy, Kaplan Ray M, Streit Thomas G, Idaghdour Youssef, Scott Marilyn E, Basáñez Maria-Gloria, Prichard Roger K

Abstract excerpt

BACKGROUND: Albendazole (ABZ), a benzimidazole (BZ) anthelmintic (AH), is commonly used for treatment of soil-transmitted helminths (STHs). Its regular use increases the possibility that BZ resistance may develop, which, in veterinary nematodes is caused by single nucleotide polymorphisms (SNPs) in the β-tubulin gene at positions 200, 167 or 198. The relative importance of these SNPs varies among the different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthelmintics
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Nematode Infections

Share to Panama

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 23738029
DOI: 10.1371/journal.pntd.0002247
PMCID: PMC3667785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between response to albendazole treatment and β-tubulin genotype frequencies in soil-transmitted helminths.PMID 23738029Read ↗

Rapid Genotyping of β-tubulin Polymorphisms in Trichuris trichiura and Ascaris lumbricoides.Semantic proximity Read ↗

The assessment of single nucleotide polymorphisms in the ß-tubulin genes in human soil-transmitted helminths exposed to different pressure with benzimidazole drugsSemantic proximity Read ↗

Assays to detect beta-tubulin codon 200 polymorphism in Trichuris trichiura and Ascaris lumbricoides.Semantic proximity Read ↗

Relationship between increased albendazole systemic exposure and changes in single nucleotide polymorphisms on the β-tubulin isotype 1 encoding gene in Haemonchus contortus.Semantic proximity Read ↗

Absence of detectable benzimidazole-resistance associated alleles in Haemonchus placei in cattle in Nigeria revealed by pyrosequencing of β-tubulin isotype 1.Semantic proximity Read ↗

Benzimidazole Resistance-Associated Mutations in the β-tubulin Gene of Hookworms: A Systematic Review.Semantic proximity Read ↗

Deep-amplicon sequencing of the complete beta-tubulin gene in Trichuris trichiura before and after albendazole treatment.Semantic proximity Read ↗

Moving beyond the state of the art of understanding resistance mechanisms in hookworms: confirming old and suggesting new associated SNPs.Semantic proximity Read ↗

Benzimidazole Resistance-Associated Mutations in the β-tubulin Gene of Hookworms: A Systematic ReviewSemantic proximity Read ↗

Development of high throughput method for the analysis of anthelmintic resistance allele frequencies in field populations of gastrointestinal nematodesSemantic proximity Read ↗

Prevalence of gastrointestinal parasites and molecular identification of beta-tubulin mutations associated with benzimidazole resistance in Haemonchus contortus in goats from selected districts of Uganda.Semantic proximity Read ↗

Quantification of resistant alleles in the β-tubulin gene of field strains of gastrointestinal nematodes and their relation with the faecal egg count reduction test.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.