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Early detection and prognosis evaluation for hepatocellular carcinoma by circulating tumour DNA methylation: A multicentre cohort study

1 May 2024

Abstract excerpt

BACKGROUND: Early diagnosis of hepatocellular carcinoma (HCC) can significantly improve patient survival. We aimed to develop a blood-based assay to aid in the diagnosis, detection and prognostic evaluation of HCC. METHODS: A three-phase multicentre study was conducted to screen, optimise and validate HCC-specific differentially methylated regions (DMRs) using next-generation sequencing and quantitative...

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Share to Cancer Genomics and Diagnostics
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Share to Hepatocellular Carcinoma Treatment and Prognosis

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PMID: 38741204
DOI: 10.1002/ctm2.1652

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