Article
The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthase.
The EMBO journal - 1 Aug 2014
Lytovchenko Oleksandr, Naumenko Nataliia, Oeljeklaus Silke, Schmidt Bernhard, von der Malsburg Karina, Deckers Markus, Warscheid Bettina, van der Laan Martin, Rehling Peter
Abstract excerpt
Mitochondrial F1Fo-ATP synthase generates the bulk of cellular ATP. This molecular machine assembles from nuclear- and mitochondria-encoded subunits. Whereas chaperones for formation of the matrix-exposed hexameric F1-ATPase core domain have been identified, insight into how the nuclear-encoded F1-domain assembles with the membrane-embedded Fo-region is lacking. Here we identified the INA complex (INAC) in the...
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