Article

Is There a Hereditary Cancer Resistance Genotype?

2026-01-22

Abstract excerpt

Most of the knowledge about germline related cancer risks emerged from pioneering studies of families with increased cancer incidence. This led to the discovery of the chapter of hereditary cancer predisposing syndromes. More than 50 syndromes have been identified and thoroughly studied. While most germline studies focused on pathogenic variants that increase cancer risk (e.g. BRCA1/2, CHEK2 with ORs up to 8.6),...

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Literature Corpus work: 5370db56-6cc4-5eb6-a0c9-1e53e0631ec4
DOI: 10.32388/dcrtzv

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