[Genetic factors involved in cancer susceptibility].

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Article

[Genetic factors involved in cancer susceptibility].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jul 2002

Kohno Takashi, Yokota Jun

Abstract excerpt

Cancers can be classified as hereditary or sporadic based on the difference in the involvement of genetic factors. Hereditary cancers, which account for approximately 2% of all cancers, are caused by germline mutations of defined genes inherited in an autosomal dominant or recessive manner. Dozens of tumor suppressor genes, oncogenes and DNA repair genes have been identified as being responsible for hereditary...

Topics

Animals
DNA Repair
Genes, Tumor Suppressor
Genetic Predisposition to Disease
Genetic Variation
Germ-Line Mutation
Humans
Mice
Neoplasms
Neoplastic Syndromes, Hereditary
Polymorphism, Genetic

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Open in PubMed

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PMID: 12146010

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