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Article

Realizing the promise of cancer predisposition genes.

Nature - 16 Jan 2014

Rahman Nazneen

Abstract excerpt

Genes in which germline mutations confer highly or moderately increased risks of cancer are called cancer predisposition genes. More than 100 of these genes have been identified, providing important scientific insights in many areas, particularly the mechanisms of cancer causation. Moreover, clinical utilization of cancer predisposition genes has had a substantial impact on diagnosis, optimized management and...

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Identifiers

PMID: 24429628
DOI: 10.1038/nature12981
PMCID: PMC4975511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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