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Influence of genetic ancestry on breast stromal cells provides biologic basis for increased incidence of metaplastic breast cancer in women of African descent

2022-07-18

Abstract excerpt

<h4>ABSTRACT</h4> The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment of a population of ZEB1-expressing cells located adjacent to the ductal epithelial cells in the normal breast of women of African Ancestry (AA) compared to European Ancestry (EA). By establishing and characterizing cell lines correspondin...

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Literature Corpus work
53663cee-3583-5b33-82cc-77abe0e28a0e
DOI
10.1101/2022.07.14.500115
Open publication

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Influence of genetic ancestry on breast stromal cells provides biologic basis for increased incidence of metaplastic breast cancer in women of African descentDOI 10.1101/2022.07.14.500115
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