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Stromal heterogeneity may explain increased incidence of metaplastic breast cancer in women of African descent

14 Sept 2023

Abstract excerpt

Abstract The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment of a population of ZEB1-expressing cells located adjacent to ductal epithelial cells in normal breasts of women of African ancestry compared to those of European ancestry. In this study, we demonstrate that these cells have properties of...

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PMID: 37709737
DOI: 10.1038/s41467-023-41473-6

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