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Elevated levels of IL-6 in IgA nephropathy patients are induced by an epigenetically driven mechanism modulated by viral and bacterial RNA

2022-03-07

Abstract excerpt

<h4>ABSTRACT</h4> Immunoglobulin A nephropathy (IgAN) is the most frequent primary glomerulonephritis characterized by the presence of IgA immune complexes in the glomeruli. Recently, a multihit model has been proposed to describe the pathogenesis of IgAN, but it is believed that further predisposing factors are present, including immunological, genetic and environmental factors. Newly, the role of IL-6 in pathoge...

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Literature Corpus work
532c3e89-0369-52f6-97b1-5971bcad6abb
DOI
10.1101/2022.03.05.22271944
Open publication

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Elevated levels of IL-6 in IgA nephropathy patients are induced by an epigenetically driven mechanism modulated by viral and bacterial RNADOI 10.1101/2022.03.05.22271944
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