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DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics

2020-07-12

Abstract excerpt

The spatiotemporal proteome of the intervertebral disc (IVD) underpins its integrity and function. We present DIPPER, a deep and comprehensive IVD proteomic resource comprising 94 genomewide profiles from 17 individuals. To begin with, protein modules defining key directional trends spanning the lateral and anteroposterior axes were derived from high-resolution spatial proteomes of intact young cadaveric lumbar IV...

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Literature Corpus work
53038d42-46b4-50e0-93e3-1fcf107ec4b0
DOI
10.1101/2020.07.11.192948
Open publication

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DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamicsDOI 10.1101/2020.07.11.192948
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