Article
Hereditary features, treatment, and prognosis of the lipoprotein glomerulopathy in patients with the APOE Kyoto mutation.
Kidney international - 1 Feb 2014
Hu Zhangxue, Huang Songmin, Wu Yu, Liu Yunqiang, Liu Xiaoxia, Su Dan, Tao Ye, Fu Ping, Zhang Xiuhui, Peng Ziying, Zhang Sizhong, Yang Yuan
Abstract excerpt
Lipoprotein glomerulopathy is a rare inherited renal disease, caused by mutation of the APOE gene, characterized by proteinuria and nephrotic syndrome with elevated serum apoE. Since its treatment and outcome are unknown, we retrospectively studied 35 patients within 31 unrelated Han families with biopsy-proven lipoprotein glomerulopathy residing in the same county in southwest China. DNA sequencing detected the...
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