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Generation of Population-Level Diversity in <i>Anaplasma phagocytophilum msp2/p44</i> Gene Repertoires Through Recombination

2025-02-11

Abstract excerpt

Anaplasma phagocytophilum, a tick-borne Rickettsiales, causes the emerging disease of humans and animals, granulocytic anaplasmosis. The organism expresses an immunodominant surface protein, MSP2/P44, that undergoes rapid antigenic variation during single infections due to gene conversion of a single genomic expression site with sequences from one of ~100 transcriptionally silent genes known as “functional pseudog...

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Literature Corpus work
529905bf-469f-59f6-882a-e965c06dc50e
DOI
10.20944/preprints202502.0781.v1
Open publication

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