Article
Distinctly different msp2 pseudogene repertoires in Anaplasma marginale strains that are capable of superinfection.
Gene - 21 Nov 2005
Rodríguez José-Luis, Palmer Guy H, Knowles Donald P, Brayton Kelly A
Abstract excerpt
Lifelong persistent infection of cattle is a hallmark of the tick transmitted pathogen Anaplasma marginale. Antigenic variation of Major Surface Protein 2 (MSP2) plays an important role in evasion of the host immune response to allow persistence. Antigenic variation of MSP2 is achieved by gene conversion of pseudogenes into the single operon linked expression site and the diversity of variants is defined by the...
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