Article

Exploring the Shared Pathophysiological Mechanisms Between Diabetic Retinopathy and High Myopia: Insights from OCTA and Bioinformatics Analysis

2025-10-17

Abstract excerpt

<title>Abstract</title> <p><bold>Objective: </bold>To investigate the common pathophysiological mechanisms between diabetic retinopathy (DR) and high myopia (HM) using optical coherence tomography angiography (OCTA) and integrated bioinformatics approaches. <bold>Methods:</bold> A total of 72 patients with type 2 diabetes were enrolled and stratified based on axial length and DR severity. OCTA was performed to ev...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5272c303-f3b2-5823-a886-114978c2cbcc
DOI: 10.21203/rs.3.rs-7482406/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploring the Shared Pathophysiological Mechanisms Between Diabetic Retinopathy and High Myopia: Insights from OCTA and Bioinformatics AnalysisDOI 10.21203/rs.3.rs-7482406/v1Read

Comprehensive Investigation of Oxidative Stress-Related Hub Genes in Proliferative Vitreoretinopathy Based on Bioinformatics AnalysisSemantic proximity Read

Identification of key biomarkers in Diabetic retinopathy and age-related macular degeneration by integrated bioinformatics analysisSemantic proximity Read

Identification of potential molecular targets associated with proliferative diabetic retinopathySemantic proximity Read

Advances in the Molecular Pathophysiology and Emerging Therapeutic Strategies for Diabetic RetinopathySemantic proximity Read

Single-cell transcriptomics-based multidisease analysis revealing the molecular dynamics of retinal neurovascular units under inflammatory and hypoxic conditionsSemantic proximity Read

RNA sequencing reveals BMP4 as a basis for the dual-target treatment of diabetic retinopathySemantic proximity Read

Differential Distribution of Fibrovascular Proliferative Membranes in 25-Gauge Vitrectomy for Proliferative Diabetic RetinopathySemantic proximity Read

Remodeling of Retinal Architecture in Diabetic Retinopathy: Disruption of Ocular Physiology and Visual Functions by Inflammatory Gene Products and PyroptosisSemantic proximity Read

A proposal for early and personalized treatment of diabetic retinopathy based on clinical pathophysiology and molecular phenotyping.Semantic proximity Read

Genetic Associations of Myopia and Axial Length with Diabetic Retinopathy.Semantic proximity Read

Identification of Dysregulated Pathways and key genes in Human Retinal Angiogenesis using Microarray MetadataSemantic proximity Read

Genetics of Diabetic Retinopathy, a Leading Cause of Irreversible Blindness in the Industrialized WorldSemantic proximity Read