Article

MAPR origins reveal a new class of prokaryotic cytochrome b <sub>5</sub> proteins and possible role in eukaryogenesis

2021-11-18

Abstract excerpt

The multiple functions of PGRMC1, the archetypal heme-binding eukaryotic MAPR family member, include steroidogenic regulation, membrane trafficking, and steroid responsiveness. The interrelationships between these functions are currently poorly understood. Previous work has shown that different MAPR subclasses were present early in eukaryotic evolution, and that tyrosine phosphorylated residues appeared in the eum...

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Literature Corpus work: 526878ea-9390-555e-9814-36207e720404
DOI: 10.1101/2021.11.17.468889

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MAPR origins reveal a new class of prokaryotic cytochrome b <sub>5</sub> proteins and possible role in eukaryogenesisDOI 10.1101/2021.11.17.468889Read

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