Membrane-bound progesterone receptors contain a cytochrome b5-like ligand-binding domain

Abstract excerpt

BACKGROUND: Membrane-associated progesterone receptors (MAPRs) are thought to mediate a number of rapid cellular effects not involving changes in gene expression. They do not show sequence similarity to any of the classical steroid receptors. We were interested in identifying distant homologs of MAPR better to understand their biological roles. RESULTS: We have identified MAPRs as distant homologs of cytochrome...

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