Article

Patient-specific simulation of Retinal Hemangioblastoma provides new perspectives on the role of antiangiogenic therapy

2023-02-27

Abstract excerpt

<h4>ABSTRACT</h4> Retinal Hemangioblastoma (RH) is the most frequent manifestation of the von Hippel-Lindau syndrome (VHL), a rare disease associated with the germline mutation of the von Hippel-Lindau protein (pVHL). An emblematic feature of RH is the high vascularity, which is easily explained by the overexpression of angiogenic factors (AFs) arising from the pVHL impairment. The introduction of Optical Coheren...

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Literature Corpus work: 523a185a-55a9-5359-ba1f-e4a2c60c2ca8
DOI: 10.1101/2023.02.24.529937

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