Article

MetaPointFinder: Detection of Antimicrobial Resistance-Conferring Point Mutations (ARMs) from Metagenomic Reads

2025-12-05

Abstract excerpt

<h4>Background: </h4> Many clinically important antimicrobial resistance (AMR) phenotypes such as fluoroquinolones and rifamycins are driven by antimicrobial resistance-conferring mutations (ARMs) in conserved chromosomal loci (e.g., gyrA , parC, rpoB ). Resistome profiling by metagenomics sequencing is often proposed as an ideal AMR surveillance tool as it is organism-agnostic, but currently, existing metagenom...

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Literature Corpus work: 522b9a8d-2b9d-5421-ad03-cd11adcdeb41
DOI: 10.64898/2025.12.04.691125

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