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Article

Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia

1 Jan 2022

Abstract excerpt

Objectives: Febrile neutropenia (FN) is a major cause of treatment disruption and unplanned hospitalization in childhood cancer patients. This study investigated the transcriptome of peripheral blood mononuclear cells (PBMCs) in children with cancer and FN to identify potential predictors of serious infection. Methods: = 28) after admission. Differentially expressed genes as well as gene pathways that correlated...

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PMID: 35602885
DOI: 10.1002/cti2.1383

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