Article

eSVD-DE: Cohort-wide differential expression in single-cell RNA-seq data using exponential-family embeddings

2023-11-23

Abstract excerpt

<h4>Background</h4> Single-cell RNA-sequencing (scRNA) datasets are becoming increasingly popular in clinical and cohort studies, but there is a lack of methods to investigate differentially expressed (DE) genes among such datasets with numerous individuals. While numerous methods exist to find DE genes for scRNA data from limited individuals, differential-expression testing for large cohorts of case and control...

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Literature Corpus work: 51d5ea59-7338-57ae-a860-3d15a9c371ba
DOI: 10.1101/2023.11.22.568369

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